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Imatinib (STI571)
SPC-01076
CAS No. 152459-95-5
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 250 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PDGFR inhibitor ; Bcr-Abl inhibitor ; c-Kit inhibitor ; Autophagy activator
| Description |
|---|
| Imatinib (STI571, CGP057148B, ST-1571) is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 152459-95-5 |
| Description | Imatinib (STI571, CGP057148B, ST-1571) is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy. |
| Formula | C29H31N7O |
| Molecular Weight | 493.6 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Glivec, CGP057148B, ST-1571 |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5 |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.