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Imatinib Mesylate (STI571)
SPC-01077
CAS No. 220127-57-1
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 100 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| 250 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Bcr-Abl inhibitor ; c-Kit inhibitor ; PDGFR inhibitor ; Autophagy activator
| Description |
|---|
| Imatinib Mesylate (STI571, CGP-57148B) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 220127-57-1 |
| Description | Imatinib Mesylate (STI571, CGP-57148B) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib Mesylate (STI571) induces autophagy. |
| Formula | C29H31N7O.CH4SO3 |
| Molecular Weight | 589.71 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Glivec, CGP-57148B, ST-1571 Mesylate |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.