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IL7R cDNA ORF Clone, Human, In cloning vector
SPD-08523
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| Full length Clone DNA of Human interleukin 7 receptor. |
| Target Information | |
|---|---|
| Species | Human |
| Target Name | IL-7 Receptor |
| Gene Abbr. | IL7R |
| Gene ID | 3575 |
| Full Name | interleukin 7 receptor |
| Alias | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
| Introduction | IL-7R, or CD127, is often used to characterize regulatory T cells or Tregs. By phenotyping, IL-7R is inversely correlated with the high levels of the hallmark Treg transcription factor FoxP3. So lowered expression of IL-7R on the cell surface along with CD25 and CD4 in addition to FoxP3 internal expression is a major and routinely used technique for Treg cell studies. IL-7R residing on the surface enables enrichment and purification of Treg populations. Antibody to IL-7R is useful for phenotyping, identification, enumeration and purification of Tregs. |
| Product Details | |
|---|---|
| Description | Full length Clone DNA of Human interleukin 7 receptor. |
| NCBI Ref Seq | NM_002185.2 |
| RefSeq ORF Size | 1380 bp |
| Sequence Information | Identical with the Gene Bank Ref. ID sequence except for the point mutation 412 G/A resulting in the amino acid Val substitution by Ile. |
| Vector | pGEM-T Vector |
| Quality Control | The plasmid is confirmed by full-length sequencing. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
| Usage | |
|---|---|
| Sequencing Primers | SP6 and T7 or M13-47 and RV-M |
| Antibiotic in E.coli | Ampicillin |
| Shipping | Each tube contains lyophilized plasmid. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.