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IL6ST cDNA ORF Clone, Human, In cloning vector
SPD-06196
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| Full length Clone DNA of Human interleukin 6 signal transducer (gp130, oncostatin M receptor). |
| Target Information | |
|---|---|
| Species | Human |
| Target Name | GP130 |
| Gene Abbr. | IL6ST |
| Gene ID | 3572 |
| Full Name | interleukin 6 signal transducer |
| Alias | CD130, CDW130, GP130, HIES4, IL-6RB |
| Introduction | GP130 is a signal-transducing subunit shared by the receptors for the IL-6 family of cytokines. The binding of a ligand to its receptor induces the dimerization of GP130, leading to activation of the Jak tyrosine kinase and to tyrosine phosphorylation of GP130. These events lead to the activation of multiple signal-transduction pathways, such as the Stat, Ras-MAPK and PI3 kinase pathways, whose activation is controlled by distinct regions of GP130. |
| Product Details | |
|---|---|
| Description | Full length Clone DNA of Human interleukin 6 signal transducer (gp130, oncostatin M receptor). |
| NCBI Ref Seq | NM_002184.3 |
| RefSeq ORF Size | 2757 bp |
| Sequence Information | Identical with the Gene Bank Ref. ID sequence except for the point mutations: 1-2 AT/CG resulting in the amino acid Met substitution by Arg, and 2757 A/C resulting in the amino acid Stop substitution by Cys. |
| Vector | pMD18-T Simple Vector |
| Quality Control | The plasmid is confirmed by full-length sequencing. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
| Usage | |
|---|---|
| Sequencing Primers | M13-47 and RV-M |
| Antibiotic in E.coli | Ampicillin |
| Shipping | Each tube contains lyophilized plasmid. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.