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IL3RA cDNA ORF Clone, Canine, In cloning vector
SPD-08200
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| Full length Clone DNA of Canine interleukin 3 receptor, alpha (low affinity). |
| Target Information | |
|---|---|
| Species | Canine |
| Target Name | IL-3 Receptor |
| Gene Abbr. | IL3RA |
| Gene ID | 609293 |
| Full Name | interleukin 3 receptor subunit alpha |
| Introduction | CD123 (Cluster of Differentiation 123), also known as Interleukin-3 receptor subunit alpha, is an Interleukin 3 specific subunit of a heterodimeric cytokine receptor. CD123 is a low affinity receptor to interleukin-3 and is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3, colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5. The CD123 beta subunit is activated by the ligand binding, and is required for the biological activities of IL-3. A member of type I cytokine receptor family and type 5 subfamily, CD123 functions as a signaling cytokine known to stimulate cell proliferation, differentiation and survival. The gene for this protein maps within the X-Y pseudoautosomal region (PAR). |
| Product Details | |
|---|---|
| Description | Full length Clone DNA of Canine interleukin 3 receptor, alpha (low affinity). |
| NCBI Ref Seq | XM_846533.3 |
| RefSeq ORF Size | 1128 bp |
| Sequence Information | Identical with the Gene Bank Ref. ID sequence except for the point mutation 1049 A/G, 1058 A/C and 1060 T/A resulting in the amino acid Lys substitution by Arg, His substitution by Pro, Trp substitution by Arg. |
| Vector | pGEM-T Vector |
| Quality Control | The plasmid is confirmed by full-length sequencing. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
| Usage | |
|---|---|
| Sequencing Primers | SP6 and T7 or M13-47 and RV-M |
| Antibiotic in E.coli | Ampicillin |
| Shipping | Each tube contains lyophilized plasmid. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.