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IL10 cDNA ORF Clone, Canine, In cloning vector
SPD-06840
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| Full length Clone DNA of Canine interleukin 10. |
| Target Information | |
|---|---|
| Species | Canine |
| Target Name | IL-10 |
| Gene Abbr. | IL10 |
| Gene ID | 403628 |
| Full Name | interleukin 10 |
| Introduction | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq] |
| Product Details | |
|---|---|
| Description | Full length Clone DNA of Canine interleukin 10. |
| NCBI Ref Seq | NM_001003077.1 |
| RefSeq ORF Size | 546 bp |
| Sequence Information | Identical with the Gene Bank Ref. ID sequence except for the point mutations: 80 T/C, 161-162 TC/CT resulting in the amino acid Leu substitution by Pro, Ile substitution by Thr and 204 C/T，399 T/G not causing the amino acid variation. |
| Vector | pGEM-T Vector |
| Quality Control | The plasmid is confirmed by full-length sequencing. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
| Usage | |
|---|---|
| Sequencing Primers | SP6 and T7 or M13-47 and RV-M |
| Antibiotic in E.coli | Ampicillin |
| Shipping | Each tube contains lyophilized plasmid. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.