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IL-7R alpha/CD127 Antibody
SPA-05963
| Size | Price |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-7 Receptor |
| Gene Abbr. | IL7R |
| Gene ID | 3575 |
| Full Name | interleukin 7 receptor |
| Alias | CD127, CDW127, IL-7R-alpha, IL7RA, ILRA |
| Introduction | IL-7R, or CD127, is often used to characterize regulatory T cells or Tregs. By phenotyping, IL-7R is inversely correlated with the high levels of the hallmark Treg transcription factor FoxP3. So lowered expression of IL-7R on the cell surface along with CD25 and CD4 in addition to FoxP3 internal expression is a major and routinely used technique for Treg cell studies. IL-7R residing on the surface enables enrichment and purification of Treg populations. Antibody to IL-7R is useful for phenotyping, identification, enumeration and purification of Tregs. |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 73N8F2 |
| Isotype | IgG2A Kappa |
| Immunogen | Amino acids 145-235 of mouse IL-7R / CD127 were used as the immunogen for the antibody. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (2-5 µg/mL); Immunohistochemistry (1:10-1:500) |
| Reactivity | Mouse |
| Storage & Handling | |
|---|---|
| Storage Buffer | 0.5 mg/mL in PBS and 0.05% BSA. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.