IL-4R alpha Antibody - CD BioSciences

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IL-4R alpha Antibody

IL-4R alpha Antibody

SPA-05926

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25 µg Online Inquiry
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Target Information
Target Name IL-4 Receptor
Gene Abbr. IL4R
Gene ID 3566
Full Name interleukin 4 receptor
Alias CD124, IL-4RA, IL4RA
Introduction Interleukin 4 receptor (IL-4 R) is the transmembrane ligand binding subunit of the heterodimeric IL-4 receptor complex. In the type I receptor complex, IL-4 R associates with the common gamma chain, whereas in the type II receptor complex, it associates with IL-13 R alpha 1. IL-4 R is expressed by B cells, T cells, monocytes and macrophages.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 25463
Isotype IgG2A
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL‑4 R. Gly24-His232. Accession # P24394.
Usage
Application WB, FC, IHC, IF
Dilutions Western Blot (1 µg/mL); Flow Cytometry (0.25 µg/10^6 cells); Immunohistochemistry (8-25 µg/mL); Immunofluorescence (5-15 µg/mL); Neutralization (3-6 ng/mL)
Reactivity Human
Specificity Detects human IL‑4 R alpha in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-9 R, recombinant mouse IL-4 R, rhIL-5 R alpha, rhIL-5 R beta, rhIL-13 R alpha 1, or rhIL-13 R alpha 2 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.