IL-4 Antibody - CD BioSciences

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IL-4 Antibody

IL-4 Antibody

SPA-05923

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Target Information
Target Name IL-4
Gene Abbr. IL4
Gene ID 3565
Full Name interleukin 4
Alias BCGF-1, BCGF1, BSF-1, BSF1, IL-4
Introduction Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13-18 kDa Th2 cytokine that shows pleiotropic effects during immune responses. It is a glycosylated polypeptide that contains three intrachain disulfide bridges and adopts a bundled four alpha -helix structure. Mouse IL-4 is synthesized with a 24 amino acid (aa) signal sequence. Mature mouse IL-4 shares 39%, 39%, and 59% aa sequence identity with bovine, human, and rat IL-4, respectively. Human, mouse, and rat IL-4 are species-specific in their activities.
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen E. coli-derived recombinant bovine IL‑4. His25-Cys135. P30367.
Usage
Application WB, IF
Dilutions Western Blot (0.1 µg/mL); Immunofluorescence (10-20 µg/mL)
Reactivity Bovine
Specificity Detects bovine IL-4 in direct ELISAs and Western Blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant porcine IL-4 is observed, less than 5% cross-reactivity with recombinant human IL-4, recombinant feline IL-4, and recombinant canine IL-4 is observed, and less than 1% cross-reactivity with recombinant mouse IL-4, recombinant rat IL-4, and recombinant rhesus macaque IL-4 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.