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IL-3R alpha/CD123 Antibody
SPA-05865
| Size | Price |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-3 Receptor |
| Gene Abbr. | IL3RA |
| Gene ID | 3563 |
| Full Name | interleukin 3 receptor subunit alpha |
| Alias | CD123, IL3R, IL3RAY, IL3RX, IL3RY |
| Introduction | CD123 (Cluster of Differentiation 123), also known as Interleukin-3 receptor subunit alpha, is an Interleukin 3 specific subunit of a heterodimeric cytokine receptor. CD123 is a low affinity receptor to interleukin-3 and is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3, colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5. The CD123 beta subunit is activated by the ligand binding, and is required for the biological activities of IL-3. A member of type I cytokine receptor family and type 5 subfamily, CD123 functions as a signaling cytokine known to stimulate cell proliferation, differentiation and survival. The gene for this protein maps within the X-Y pseudoautosomal region (PAR). |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 18N6B12 |
| Isotype | IgG2B Kappa |
| Immunogen | A portion of amino acids 250-300 of human CD123 was used as the immunogen for this antibody. |
| Usage | |
|---|---|
| Application | WB, FC |
| Dilutions | Western Blot (10 µg/mL); Flow Cytometry (1 µg/0.5x10^6 cells) |
| Reactivity | Human |
| Storage & Handling | |
|---|---|
| Storage Buffer | 0.2 mL PBS and 0.05% BSA. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.