IL-3R alpha/CD123 Antibody - CD BioSciences

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IL-3R alpha/CD123 Antibody

IL-3R alpha/CD123 Antibody

SPA-05864

Size Price
0.1 mg Online Inquiry
More Options Online Inquiry
Target Information
Target Name IL-3 Receptor
Gene Abbr. IL3RA
Gene ID 3563
Full Name interleukin 3 receptor subunit alpha
Alias CD123, IL3R, IL3RAY, IL3RX, IL3RY
Introduction CD123 (Cluster of Differentiation 123), also known as Interleukin-3 receptor subunit alpha, is an Interleukin 3 specific subunit of a heterodimeric cytokine receptor. CD123 is a low affinity receptor to interleukin-3 and is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3, colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5. The CD123 beta subunit is activated by the ligand binding, and is required for the biological activities of IL-3. A member of type I cytokine receptor family and type 5 subfamily, CD123 functions as a signaling cytokine known to stimulate cell proliferation, differentiation and survival. The gene for this protein maps within the X-Y pseudoautosomal region (PAR).
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 107D2.08
Isotype IgG1
Immunogen IL3R Alpha/ CD123 was used as immunogen.
Usage
Application WB, FC, IHC, IP
Dilutions Western Blot (1:100-1:2000); Flow Cytometry (1:10-1:1000); Immunohistochemistry (1:10-1:500); Immunoprecipitation (1:10-1:500)
Reactivity Human, Canine
Storage & Handling
Storage Buffer Tris-NaCl (pH 8.0).
Preservative No Preservative
Storage Temp. Store at -20 °C.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.