IL-32 Antibody - CD BioSciences

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IL-32 Antibody

IL-32 Antibody

SPA-05882

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Target Information
Target Name IL-32
Gene Abbr. IL32
Gene ID 9235
Full Name interleukin 32
Alias IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4
Introduction Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-alpha, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFNgamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human IL-32.
Usage
Application WB
Reactivity Human
Storage & Handling
Storage Buffer 0.2 µm filtered solution in PBS.
Preservative No Preservative
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.