IL-27 Antibody - CD BioSciences

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IL-27 Antibody

IL-27 Antibody

SPA-05847

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Target Information
Target Name IL-27
Gene Abbr. IL27
Gene ID 246778
Full Name interleukin 27
Alias IL-27, IL-27A, IL27A, IL27p28, IL30
Introduction The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq]
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse IL-27 p28/IL-30. Phe29-Ser234. Accession # Q8K3I6.
Usage
Application WB, IHC
Dilutions Western Blot (0.1 µg/mL); Immunohistochemistry (5-15 µg/mL); Neutralization (1-5 µg/mL)
Reactivity Mouse
Specificity Detects mouse IL-27 p28/IL-30 in direct ELISAs and Western Blots.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.