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IL-24 Antibody
SPA-05838
| Size | Price |
| 0.025 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-24 |
| Gene Abbr. | IL24 |
| Gene ID | 11009 |
| Full Name | interleukin 24 |
| Alias | C49A, FISP, IL10B, MDA7, MOB5 |
| Introduction | Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radio sensitization in malignant gliomas in a p53-independent manner. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Amino acids 123-136 (KNYHNRTVEVRTLK) of human IL-24 were used as the immunogen for this antibody. |
| Usage | |
|---|---|
| Application | WB, FC |
| Dilutions | Western Blot (0.5-3 µg/mL); Flow Cytometry (2-5 µg/10^6 cells) |
| Reactivity | Human, Primate |
| Specificity | The amino acid sequence used as immunogen is found in many of the IL-24 isoforms, including isoforms of 219, 207, 206, 154, 143 and 120 amino acids. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS containing 0.2% gelatin. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.