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IL-23A/IL-23 P19 Antibody
SPA-05831
Size | Price |
25 µg | Online Inquiry |
50 µg | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | IL-23 |
Gene Abbr. | IL23A |
Gene ID | 51561 |
Full Name | interleukin 23 subunit alpha |
Alias | IL-23, IL-23A, IL23P19, P19, SGRF |
Introduction | Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. |
Product Details | |
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Host | Mouse |
Clonality | Monoclonal |
Clone No. | 727753 |
Isotype | IgG2B |
Immunogen | E. coli-derived recombinant human IL-23 p19. Arg20-Pro189. Q9NPF7. |
Usage | |
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Application | WB, FC |
Dilutions | Western Blot (1 µg/mL); Flow Cytometry (2.5 µg/10^6 cells) |
Reactivity | Human |
Specificity | Detects human IL-23 p19 in direct ELISAs and Western Blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human (rh) IL-23 heterodimer is observed, less than 10% cross-reactivity with recombinant mouse (rm) IL-23 heterodimer is observed, and no cross-reactivity with recombinant feline IL-23 p19, recombinant canine (rca) IL-23 p19, and recombinant rat IL-23 p19 is observed. In Western Blots, no cross-reactivity with rcaIL-23 p19 or rmIL-23 p19 is observed. |
Storage & Handling | |
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Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
Preservative | No Preservative |
Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.