IL-21R Antibody - CD BioSciences

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IL-21R Antibody

IL-21R Antibody

SPA-05791

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Target Information
Target Name IL-21 Receptor
Gene Abbr. IL21R
Gene ID 50615
Full Name interleukin 21 receptor
Alias CD360, IMD56, NILR
Introduction A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. Both IL-21R and the gammac are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Product Details
Host Rabbit
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Synthetic peptide: CVLETRSPNPSILSLTWQDEYEELQDQETF, corresponding to N-term amino acids 35-65 of Mouse IL21 Receptor.
Usage
Application ELISA, IHC
Dilutions ELISA (1:100000); Immunohistochemistry (1:10-1:500)
Reactivity Mouse, Human, Rat
Specificity IL21 Receptor.
Storage & Handling
Storage Buffer PBS (pH 7.2).
Preservative 0.1% Sodium Azide
Storage Temp. Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage.
Handling Avoid freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.