Online Inquiry
IL-20R alpha Antibody
SPA-05781
| Size | Price |
| 25 µg | Online Inquiry |
| 500 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-20 Receptor |
| Gene Abbr. | IL20RA |
| Gene ID | 53832 |
| Full Name | interleukin 20 receptor subunit alpha |
| Alias | CRF2-8, IL-20R-alpha, IL-20R1, IL-20RA |
| Introduction | IL20R is a member of Cytokine Class II receptor super family. It consists of a central transmembrane domain and functionally induces IL20 and IL26 signaling in epithelial cells and keratinocytes. It associates with IL-20RB and forms a functional receptor complex for IL20, IL19, and IL24. It also associates with IL-10RB and forms a unique heterodimeric functional receptor complex for IL-26. Upon ligand binding, it induces signaling through activation of STAT3 and STAT1. IL20RA is specifically expressed in skin suggesting a prominent role in growth and proliferation of keratinocytes. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 173707 |
| Isotype | IgG1 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IL-20 R alpha. Val30-Lys250. Accession # Q9UHF4. |
| Usage | |
|---|---|
| Application | IHC |
| Dilutions | Immunohistochemistry (8-25 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human IL-20 R alpha in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, 100% cross-reactivity with recombinant mouse (rm) IL-20 R alpha is observed and no cross-reactivity with rmIFN-alpha / beta R2, recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, rhIL-10 R beta, or rhIL‑20 R beta is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.