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IL-17RD/SEF Antibody
SPA-05706
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-17 Receptor |
| Gene Abbr. | IL17RD |
| Gene ID | 54756 |
| Full Name | interleukin 17 receptor D |
| Alias | HH18, IL-17RD, IL17RLM, SEF |
| Introduction | Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. The gene for this protein belongs to a synexpression group originally identified in zebrafish and SEF is expressed along with FGF-3, -8, sprouty-2 (SPRY2) and SPRY4. Due to the presence of an alternate start site, there is one transcript that potentially gives rise to two isoforms. The first is a full-length long form and the second an N-terminally truncated form. The significance and expression pattern of the short form are uncertain. |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse IL‑17 RD/SEF. Gly28-Arg299. Accession # Q8JZL1. |
| Usage | |
|---|---|
| Application | WB, FC, IHC |
| Dilutions | Western Blot (0.1 µg/mL); Flow Cytometry (0.25 µg/10^6 cells); Immunohistochemistry (5-15 µg/mL) |
| Reactivity | Mouse |
| Specificity | Detects mouse IL-17 RD/SEF in direct ELISAs and Western Blots. In direct ELISAs, approximately 40% cross-reactivity with recombinant human IL-17 RD is observed and less than 1% cross-reactivity with recombinant mouse (rm) IL-17 RC and rmIL-17B R is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.