IL-17RB Antibody - CD BioSciences

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IL-17RB Antibody

IL-17RB Antibody

SPA-05696

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Target Information
Target Name IL-17 Receptor
Gene Abbr. IL17RB
Gene ID 55540
Full Name interleukin 17 receptor B
Alias CRL4, EVI27, IL17BR, IL17RH1
Introduction The interleukin 17 (IL-17) family of cytokines, comprising six members (IL-17, IL-17B through IL-17F), are structurally related proteins with a conserved cysteine-knot structure. These proinflammatory cytokines can induce local cytokine productions and are involved in the regulation of the immune response. The cognate receptors activated by some of these cytokines have been identified. Interleukin-17 B Receptor (IL-17 RB), also known as IL-17Rh1, IL-17ER and EVI27, represents the second receptor of the IL-17 family of cytokines to be recognized.
Product Details
Host Rat
Clonality Monoclonal
Clone No. 152316
Isotype IgG2B
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse IL‑17 RB. Arg18-Gly286 (predicted). Accession # Q9JIP3.
Usage
Application WB
Dilutions Western Blot (1 µg/mL)
Reactivity Mouse
Specificity Detects mouse IL‑17 RB in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL‑17 RA/IL‑17 R, recombinant mouse IL-17 RA/IL-17 R, or rhIL-17 RB is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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