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IL-17RA/IL-17R Antibody
SPA-05688
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IL-17 Receptor |
| Gene Abbr. | IL17RA |
| Gene ID | 23765 |
| Full Name | interleukin 17 receptor A |
| Alias | CANDF5, CD217, CDw217, IL-17RA, IL17R |
| Introduction | IL-17 R, also known as IL-17 RA, is a 120 kDa type I transmembrane glycoprotein protein that plays a central role in inflammatory responses. Mature mouseIL‑17 R consists of a 291 amino acid (aa) extracellular domain, a 21 aa transmembrane segment, and a 521 aa cytoplasmic domain. The cytoplasmic domain contains a region homologous to the TIR domain of the TLR/IL-1 R family. |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 657603 |
| Isotype | IgG2A |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse IL‑17 RA/IL‑17 R. Ser32-Trp322. Accession # Q60943. |
| Usage | |
|---|---|
| Application | FC |
| Dilutions | Flow Cytometry (2.5 µg/10^6 cells); Neutralization (0.2-0.8 µg/mL) |
| Reactivity | Mouse |
| Specificity | Detects mouse IL‑17 RA/IL‑17 R in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human IL-17 RA, recombinant mouse (rm) IL-17B R, rmIL-17 RD, or rmIL-17 RC is observed. In Western Blots, less than 10% cross‑reactivity with recombinant human (rh) IL-17 RA or rhIL-17B R is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.