IL-15 Antibody - CD BioSciences

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IL-15 Antibody

IL-15 Antibody

SPA-05640

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Target Information
Target Name IL-15
Gene Abbr. IL15
Gene ID 3600
Full Name interleukin 15
Alias IL-15
Introduction Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2. The dominant mechanism of IL-15 action is known as transpresentation in which IL-15 and IL-15 R alpha are coordinately expressed on the surface of one cell and interact with complexes of IL-2 R beta/gamma c on adjacent cells. This enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Soluble IL-15-binding forms of IL-15 R alpha can be generated by proteolytic shedding or alternate splicing.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 34559
Isotype IgG1
Immunogen E. coli-derived recombinant human IL-15. Asn49-Ser162. P40933.
Usage
Application WB, FC
Dilutions Western Blot (1 µg/mL); Flow Cytometry (2.5 µg/10^6 cells); Neutralization (0.1-0.5 µg/mL)
Reactivity Human
Specificity Detects human IL-15 in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2, recombinant mouse IL-15, or rhIL-21 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.