IL-10 R beta Antibody - CD BioSciences

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IL-10 R beta Antibody

IL-10 R beta Antibody

SPA-05603

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Target Information
Target Name IL-10 Receptor
Gene Abbr. IL10RB
Gene ID 3588
Full Name interleukin 10 receptor subunit beta
Alias CDW210B, CRF2-4, CRFB4, D21S58, D21S66
Introduction The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 90220
Isotype IgG1
Immunogen Mouse myeloma cell line NS0-derived recombinant human IL-10 R beta. Met20-Ser220. Accession # Q08334.
Usage
Application WB, FC
Dilutions Western Blot (1 µg/mL); Flow Cytometry (0.25 µg/10^6 cells); Neutralization (0.5-2 µg/mL)
Reactivity Human
Specificity Detects human IL-10 R beta in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL‑10 R alpha, rhIFN-gamma RI, and rhIFN-gamma R2 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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