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IL-10 R beta Antibody
SPA-05603
Size | Price |
25 µg | Online Inquiry |
100 µg | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | IL-10 Receptor |
Gene Abbr. | IL10RB |
Gene ID | 3588 |
Full Name | interleukin 10 receptor subunit beta |
Alias | CDW210B, CRF2-4, CRFB4, D21S58, D21S66 |
Introduction | The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. |
Product Details | |
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Host | Mouse |
Clonality | Monoclonal |
Clone No. | 90220 |
Isotype | IgG1 |
Immunogen | Mouse myeloma cell line NS0-derived recombinant human IL-10 R beta. Met20-Ser220. Accession # Q08334. |
Usage | |
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Application | WB, FC |
Dilutions | Western Blot (1 µg/mL); Flow Cytometry (0.25 µg/10^6 cells); Neutralization (0.5-2 µg/mL) |
Reactivity | Human |
Specificity | Detects human IL-10 R beta in direct ELISAs and Western Blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL‑10 R alpha, rhIFN-gamma RI, and rhIFN-gamma R2 is observed. |
Storage & Handling | |
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Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
Preservative | No Preservative |
Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.