IGFBP-3 Antibody - CD BioSciences

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IGFBP-3 Antibody

IGFBP-3 Antibody

SPA-05438

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Target Information
Target Name IGFBP-3
Gene Abbr. IGFBP3
Gene ID 3486
Full Name insulin like growth factor binding protein 3
Alias BP-53, IBP3
Introduction This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Peptide with sequence C-RYKVDYESQSTDTQN corresponding to internal region according to NP_000589.2.
Usage
Application WB, ELISA
Dilutions Western Blot (0.02-0.06 µg/mL); ELISA (1:64000)
Reactivity Human, Mouse, Rat, Canine
Specificity This antibody is expected to recognise both reported isoforms (NP_001013416.1 and NP_000589.2).
Storage & Handling
Storage Buffer Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA.
Preservative 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Avoid freeze-thaw cycles.

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