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IGFBP-1 Antibody
SPA-05431
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IGFBP-1 |
| Gene Abbr. | IGFBP1 |
| Gene ID | 3484 |
| Full Name | insulin like growth factor binding protein 1 |
| Alias | AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1 |
| Introduction | The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and at least four additional low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-transitional modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 33627 |
| Isotype | IgG1 |
| Immunogen | E. coli-derived recombinant human IGFBP-1. |
| Usage | |
|---|---|
| Application | WB, ELISA |
| Dilutions | Western Blot (1 µg/mL); ELISA Capture (2-8 µg/mL); ELISA Detection (0.1-0.4 µg/mL); Neutralization (10-40 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human IGFBP-1 in ELISAs and Western Blots. In Western Blots, detection of recombinant mouse IGFBP-1 is observed but no cross‑reactivity with recombinant human (rh) IGFBP‑2, rhIGFBP‑3, rhIGFBP‑4 or rhIGFBP-5 is observered. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.