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IGF-II R/IGF2R Antibody
SPA-05417
| Size | Price |
| 0.025 mL | Online Inquiry |
| 0.1 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IGF Receptor |
| Gene Abbr. | IGF2R |
| Gene ID | 3482 |
| Full Name | insulin like growth factor 2 receptor |
| Alias | CD222, CI-M6PR, CIMPR, M6P-R, M6P/IGF2R |
| Introduction | The Cation independent Mannose 6 Phosphate Receptor transports phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose 6 phosphate receptors in the Golgi apparatus and the resulting receptor ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 2G11 |
| Isotype | IgG2A Kappa |
| Immunogen | Purified bovine Mannose 6 Phosphate Receptor (Cation independent) [UniProt# P08169]. |
| Usage | |
|---|---|
| Application | WB, ELISA, FC, IF, IHC, IP |
| Dilutions | Western Blot (1 µg/mL); Flow Cytometry (1 µg/10^6 cells); Immunofluorescence (1:10-1:250); Immunohistochemistry (1:100); Immunoprecipitation (1:10-1:500) |
| Reactivity | Human, Mouse, Rat, Bovine, Primate |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.