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IFN-gamma Antibody
SPA-06437
| Size | Price |
| 100 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Interferon |
| Gene Abbr. | IFNG |
| Gene ID | 3458 |
| Full Name | interferon gamma |
| Alias | IFG, IFI, IMD69 |
| Introduction | Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 45-15 |
| Isotype | IgG1 Kappa |
| Immunogen | IFN gamma Receptor beta. |
| Usage | |
|---|---|
| Application | ELISA, FC |
| Dilutions | ELISA (1:100-1:2000); Flow Cytometry (1:10-1:1000) |
| Reactivity | Human |
| Specificity | This antibody recognizes both the recombinant and the natural form of human interferongamma (IFN-gamma) 1. This antibody does not react with human IL-4, IFN-alpha or acid inactivated IFN-gamma. It shows only a minimal reactivity with heat-inactivated IFN-gamma (<0.05%)1. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS (pH 8.0). |
| Preservative | 0.1% Sodium Azide |
| Storage Temp. | Store at 4 °C. |
| Handling | Do not freeze. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.