Online Inquiry
IFN-beta Antibody
SPA-06413
Size | Price |
25 µg | Online Inquiry |
100 µg | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
---|---|
Target Name | Interferon |
Gene Abbr. | IFNB1 |
Gene ID | 3456 |
Full Name | interferon beta 1 |
Alias | IFB, IFF, IFN-beta, IFNB |
Introduction | Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS. |
Product Details | |
---|---|
Host | Rabbit |
Clonality | Polyclonal |
Clone No. | N/A |
Isotype | IgG |
Immunogen | Chinese hamster ovary cell line CHO-derived recombinant rat IFN-beta. |
Usage | |
---|---|
Reactivity | Rat |
Specificity | Neutralizes both natural and recombinant rat interferon beta. Cross-reactivity with human interferon beta has not been tested. |
Storage & Handling | |
---|---|
Storage Buffer | 0.5 mL Phosphate-buffered saline (PBS) and 125 mM trehalose prior to lyophilization. |
Preservative | No Preservative |
Storage Temp. | Upon receipt, this product is stable at 4 °C until the expiration date listed above. After reconstitution, the contents can be safely stored at 4 °C for one month or at -20 °C for one year for retention of full activity.When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Add 0.02% sodium azide to prevent bacterial growth. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.