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IFN-beta Antibody
SPA-06406
| Size | Price |
| 0.1 mg | Online Inquiry |
| 0.025 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Interferon |
| Gene Abbr. | IFNB1 |
| Gene ID | 3456 |
| Full Name | interferon beta 1 |
| Alias | IFB, IFF, IFN-beta, IFNB |
| Introduction | Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | A peptide corresponding to 17 amino acids near the center of human IFN-beta. The immunogen is located within amino acids 110-160 of IFN-beta. Amino Acid Sequence: LEEKLEKEDFTRGKRMS. |
| Usage | |
|---|---|
| Application | WB, ELISA, IF, IHC, IF |
| Dilutions | Western Blot (4-10 µg/mL); ELISA (1:100-1:2000); Immunofluorescence (20 µg/mL); Immunohistochemistry (2.5 µg/mL); Immunofluorescence (20 µg/mL) |
| Reactivity | Human, Mouse, Rat |
| Specificity | Human IFN-beta has one (187aa, 22kD). Mouse IFN-beta has one isoform (182aa, 22kD) and Rat IFN-beta also has one isoform (184aa, 22kD). This antibody can detect human isoform, and possibly detect mouse and rat. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.