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Iduronate 2-Sulfatase/IDS Antibody
SPA-05390
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Iduronate 2-Sulfatase |
| Gene Abbr. | IDS |
| Gene ID | 3423 |
| Full Name | iduronate 2-sulfatase |
| Alias | ID2S, MPS2, SIDS |
| Introduction | Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq]. |
| Product Details | |
|---|---|
| Host | Goat |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human IDS. Ser26-Pro550. Accession # P22304. |
| Usage | |
|---|---|
| Application | WB, IP |
| Dilutions | Western Blot (1 µg/mL); Immunoprecipitation (25 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human IDS in direct ELISAs and Western Blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse IDS is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.