ICAP-1 Antibody - CD BioSciences

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ICAP-1 Antibody

ICAP-1 Antibody

SPA-05377

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Target Information
Target Name ICAP-1
Gene Abbr. ITGB1BP1
Gene ID 9270
Full Name integrin subunit beta 1 binding protein 1
Alias ICAP-1A, ICAP-1B, ICAP-1alpha, ICAP1, ICAP1A
Introduction The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. [provided by RefSeq]
Product Details
Host Sheep
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen E. coli-derived recombinant human ICAP-1. Met1-Tyr127. O14713.
Usage
Application WB, IHC
Dilutions Western Blot (2 µg/mL); Immunohistochemistry (5-15 µg/mL)
Reactivity Human
Specificity Detects human ICAP-1 in direct ELISAs and Western Blots.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.