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Homoharringtonine
SPC-01038
CAS No. 26833-87-4
| Size | Price |
| 1 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
STAT inhibitor
| Description |
|---|
| Homoharringtonine, a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 26833-87-4 |
| Description | Homoharringtonine, a plant alkaloid with antitumor properties, inhibits protein translation by preventing the initial elongation step of protein synthesis via an interaction with the ribosomal A-site. Homoharringtonine reversiblely inhibits IL-6-induced STAT3 Tyrosine 705 phosphorylation and reduced anti-apoptotic proteins expression. |
| Formula | C29H39NO9 |
| Molecular Weight | 545.62 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Omacetaxine mepesuccinate |
| SMILES | CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.