HDM201 (Siremadlin) - CD BioSciences

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HDM201 (Siremadlin)

HDM201 (Siremadlin)

SPC-01017

HDM201 (Siremadlin)

CAS No. 1448867-41-1

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Mdm2 inhibitor

Description
HDM201 (Siremadlin, NVP-HDM201) is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.
Product Details
CAS No. CAS No. 1448867-41-1
Description HDM201 (Siremadlin, NVP-HDM201) is a novel, highly potent and selective inhibitor of the p53-Mdm2 interaction with affinity constant for Mdm2 in the picomolar range and a selectivity ratio greater than 10000-fold vs Mdm4.
Formula C26H24Cl2N6O4
Molecular Weight 555.41
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms NVP-HDM201
SMILES CC(C)N1C2=C(C(=O)N(C2C3=CC=C(C=C3)Cl)C4=CC(=CN(C4=O)C)Cl)N=C1C5=CN=C(N=C5OC)OC
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.