H3B-6527 - CD BioSciences

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H3B-6527

H3B-6527

SPC-01009

H3B-6527

CAS No. 1702259-66-2

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FGFR inhibitor

Description
H3B-6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1.2 nM and at least 250-fold selectivity over FGFR1-3 (IC50 values of 320, 1,290 and 1,060 nM respectively).
Product Details
CAS No. CAS No. 1702259-66-2
Description H3B-6527 is a highly selective covalent FGFR4 inhibitor with an IC50 value of <1.2 nM and at least 250-fold selectivity over FGFR1-3 (IC50 values of 320, 1,290 and 1,060 nM respectively).
Formula C29H34Cl2N8O4
Molecular Weight 629.54
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CCN1CCN(CC1)C2=CC(=C(C=C2)NC3=CC(=NC=N3)N(C)C(=O)NC4=C(C(=CC(=C4Cl)OC)OC)Cl)NC(=O)C=C
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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