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GW5074
SPC-00999
CAS No. 220904-83-6
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
5 mg | Online Inquiry |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
Raf inhibitor; Apoptosis related inhibitor
Description |
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GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis. |
Product Details | |
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CAS No. | CAS No. 220904-83-6 |
Description | GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis. |
Formula | C15H8Br2INO2 |
Molecular Weight | 520.94 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | C1=CC2=C(C=C1I)C(=CC3=CC(=C(C(=C3)Br)O)Br)C(=O)N2 |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.