GW5074 - CD BioSciences

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GW5074

GW5074

SPC-00999

GW5074

CAS No. 220904-83-6

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10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
25 mg Online Inquiry
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Raf inhibitor; Apoptosis related inhibitor

Description
GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis.
Product Details
CAS No. CAS No. 220904-83-6
Description GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM, no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms is noted. GW5074 inhibits LK-induced apoptosis.
Formula C15H8Br2INO2
Molecular Weight 520.94
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1=CC2=C(C=C1I)C(=CC3=CC(=C(C(=C3)Br)O)Br)C(=O)N2
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.