GW441756 - CD BioSciences

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GW441756

GW441756

SPC-00997

GW441756

CAS No. 504433-23-2

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Trk receptor inhibitor ; Apoptosis related activator ; Caspase activator

Description
GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.
Product Details
CAS No. CAS No. 504433-23-2
Description GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2. GW441756 produces a relevant increase of caspase-3 that leads to apoptosis.
Formula C17H13N3O
Molecular Weight 275.3
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.