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GSKIP (-) Cell Line
SPL-01587
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| GSKIP (-) |
| Target Information | |
|---|---|
| Target Name | GSKIP |
| Gene Abbr. | GSKIP |
| Gene ID | 51527 |
| Full Name | GSK3B interacting protein |
| Alias | C14orf129, HSPC210 |
| Species | Human |
| Introduction | This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]. |
| Product Details | |
|---|---|
| Cell Line Model | HAP1 |
| Genotype | GSKIP (-) |
| Description | GSKIP (-) |
| Parental Cell Line | C631 |
| Handling Specifications | |
|---|---|
| Disclaimer | This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.