Growth Hormone Receptor Sandwich ELISA Kit - CD BioSciences

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Growth Hormone Receptor Sandwich ELISA Kit

Growth Hormone Receptor Sandwich ELISA Kit

SPK-00438

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Target Information
Target Name Growth Hormone Receptor
Gene Abbr. Ghr
Gene ID 14600
Full Name growth hormone receptor
Alias GHB, GHBP, GHR/, GHR/BP
Introduction This gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.
Product Details
Measurement Sandwich
Usage
Application ELISA
Reactivity
Assay Principle quantitative
Sensitivity 3.9 pg/mL
Detection Range 15.6 pg/mL - 1000 pg/mL
Sample Volume 50-100μL
Assay Time 1-5h
Detection Wavelength 450 nm
Precision Intra-assay Precision (Precision within an assay): CV%<8%.
Inter-assay Precision (Precision between assays): CV%<10%.
Storage & Handling
Storage Temp. Store at 2-8°C. Please refer to protocol.

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