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GM-CSFR alpha Antibody
SPA-04554
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | GM-CSF Receptor |
| Gene Abbr. | CSF2RA |
| Gene ID | 1438 |
| Full Name | colony stimulating factor 2 receptor subunit alpha |
| Alias | CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY |
| Introduction | GM-CSF R alpha, also known as CD116, is a component of the receptor complex that mediates cellular responses to GM-CSF. GM-CSF promotes the differentiation and mobilization of granulocyte-macrophage, erythroid, megakaryocyte, and eosinophil progenitors. It enhances the activation of myeloid cell effector functions and plays a role in the development of Th1 biased immune responses, allergic inflammation, and autoimmunity. |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 698423 |
| Isotype | IgG2A |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse GM-CSF R alpha. Leu30-Pro327. Accession # Q00941. |
| Usage | |
|---|---|
| Application | FC, IF |
| Dilutions | Flow Cytometry (0.25 µg/10^6 cells); Immunofluorescence (8-25 µg/mL); Neutralization (0.02-0.12 µg/mL) |
| Reactivity | Mouse |
| Specificity | Detects mouse GM-CSF R alpha in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) GM-CSF R alpha or rhGM-CSF R beta is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.