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GilZ Antibody
SPA-04449
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | GilZ |
| Gene Abbr. | TSC22D3 |
| Gene ID | 1831 |
| Full Name | TSC22 domain family member 3 |
| Alias | DIP, DSIPI, GILZ, TSC-22R |
| Introduction | GILZ is a leucine-zipper-containing protein that is induced by glucocorticoids. It is expressed in mast cells, monocytes, macrophages, dendritic cells, and T cells. GILZ has been shown to inhibit production of IL-2 as well as TCR-driven upregulation of FasL. GILZ mediates these changes in transcription, at least in part, by inhibiting DNA-binding of the transcription factors AP-1 and NF-kB. GILZ has also been shown to mediate antiinflammatory signals in macrophages and dendritic cells by interfering with NF-kB-mediated signaling. Although GILZ has been reported to localize to the nucleus, more recent reports as well as testing have observed predominantly cytoplasmic staining. |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | CFMKG15 |
| Isotype | IgG2A Kappa |
| Immunogen | The immunogen for this antibody is GILZ. |
| Usage | |
|---|---|
| Application | WB, FC |
| Dilutions | Western Blot (1:100-1:2000) |
| Reactivity | Mouse |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS (pH 7.2). |
| Preservative | 0.09% Sodium Azide |
| Storage Temp. | Store at 4 °C. |
| Handling | Do not freeze. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.