Ghrelin/Obestatin Antibody - CD BioSciences

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Ghrelin/Obestatin Antibody

Ghrelin/Obestatin Antibody

SPA-04433

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Target Information
Target Name Ghrelin
Gene Abbr. GHRL
Gene ID 51738
Full Name ghrelin and obestatin prepropeptide
Alias MTLRP
Introduction Mature Ghrelin peptides are the result of the clavage of the Ghrelin/Obestatin Prepropeptide, a 117 aa precursor peptide that is processed into three chains, Ghrelin-27 (aa 24-50), Ghrelin-28 (aa24-51) and Obestatin (aa76-98). The prepropeptide is cleaved into proGhrelin, and then further processed into mature Ghrelin by prohormone convertases. Mature Ghrelin is acylated with an N-octanoyl group on serine 3 which is required for receptor binding. Ghrelin and Obestatin are predominantly synthesized in the gastric mucosa. Ghrelin plays a role in growth factor release and appetite suppression as well as many other functions in a variety of organs. Obestatin is a putative hormone that has been suggested to have opposite effects on growth factor release and appetite as Ghrelin.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 226706
Isotype IgG2B
Immunogen Synthetic peptide containing human Ghrelin/Obestatin. Q9UBU3.
Usage
Application ELISA
Reactivity Human
Specificity Detects human Ghrelin/Obestatin in direct ELISAs.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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