Gedatolisib (PKI-587) - CD BioSciences

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Gedatolisib (PKI-587)

Gedatolisib (PKI-587)

SPC-00934

Gedatolisib (PKI-587)

CAS No. 1197160-78-3

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PI3K inhibitor ; mTOR inhibitor

Description
Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.
Product Details
CAS No. CAS No. 1197160-78-3
Description Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.
Formula C32H41N9O4
Molecular Weight 615.73
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms PF-05212384
SMILES CN(C)C1CCN(CC1)C(=O)C2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)C4=NC(=NC(=N4)N5CCOCC5)N6CCOCC6
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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