Online Inquiry
GDC-0349
SPC-00929
CAS No. 1207360-89-1
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
5 mg | Online Inquiry |
Bulk Size | Online Inquiry |
mTOR inhibitor
Description |
---|
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1. |
Product Details | |
---|---|
CAS No. | CAS No. 1207360-89-1 |
Description | GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1. |
Formula | C24H32N6O3 |
Molecular Weight | 452.55 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | RG-7603 |
SMILES | CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(CCN(C3)C4COC4)C(=N2)N5CCOCC5C |
Solubility | DMSO |
Usage | |
---|---|
Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.