Gandotinib (LY2784544) - CD BioSciences

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Gandotinib (LY2784544)

Gandotinib (LY2784544)

SPC-00922

Gandotinib (LY2784544)

CAS No. 1229236-86-5

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JAK inhibitor

Description
Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Product Details
CAS No. CAS No. 1229236-86-5
Description Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Formula C23H25ClFN7O
Molecular Weight 469.94
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1=CC(=NN1)NC2=NN3C(=C(N=C3C(=C2)CN4CCOCC4)C)CC5=C(C=C(C=C5)Cl)F
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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