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Gambogic Acid
SPC-00921
CAS No. 2752-65-0
| Size | Price |
| 5 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Bcl-2 inhibitor ; Caspase activator
| Description |
|---|
| Gambogic Acid (Guttatic, Guttic) activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 2752-65-0 |
| Description | Gambogic Acid (Guttatic, Guttic) activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively. |
| Formula | C38H44O8 |
| Molecular Weight | 628.75 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Guttatic Acid, Guttic Acid |
| SMILES | CC(=CCCC1(C=CC2=C(C3=C(C(=C2O1)CC=C(C)C)OC45C6CC(C=C4C3=O)C(=O)C5(OC6(C)C)CC=C(C)C(=O)O)O)C)C |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.