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G-CSFR/CD114 Antibody
SPA-04271
| Size | Price |
| 25 µg | Online Inquiry |
| 500 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | G-CSF Receptor |
| Gene Abbr. | CSF3R |
| Gene ID | 1441 |
| Full Name | colony stimulating factor 3 receptor |
| Alias | CD114, GCSFR, SCN7 |
| Introduction | The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 38643 |
| Isotype | IgG1 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human G-CSF R/CD114. Glu25-Pro621. Accession # Q99062. |
| Usage | |
|---|---|
| Application | WB, FC, ELISA |
| Dilutions | Western Blot (0.5 µg/mL); Flow Cytometry (2.5 µg/10^6 cells); ELISA Capture (2-8 µg/mL); ELISA Detection (0.1-0.4 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human G-CSF R/CD114 in ELISAs and Western Blots. In sandwich Immunoassays, no cross-reactivity with recombinant human (rh) G‑CSF, rhGM‑CSF R beta, rhGM‑CSF R, or recombinant mouse G‑CSF is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.