G-CSF Antibody - CD BioSciences

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G-CSF Antibody

G-CSF Antibody

SPA-04267

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Target Information
Target Name G-CSF
Gene Abbr. CSF3
Gene ID 1440
Full Name colony stimulating factor 3
Alias C17orf33, CSF3OS, GCSF
Introduction G-CSF is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is produced mainly by monocytes and macrophages upon activation by endotoxin, TNF-alpha and IFN-gamma. Other cell types including fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells can also secrete G-CSF after LPS, IL-1, or TNF-alpha activation. In addition, various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively.
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen E. coli-derived recombinant human G-CSF. Thr31-Pro204. NP_757373.
Usage
Application WB
Dilutions Western Blot (0.1 µg/mL); Neutralization (0.02-0.1 µg/mL)
Reactivity Human
Specificity Detects human G-CSF in direct ELISAs and Western Blots. In direct ELISAs and Western Blots, less than 30% cross-reactivity with recombinant mouse G-CSF and recombinant canine G-CSF is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.