Frizzled-4 Antibody - CD BioSciences

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Frizzled-4 Antibody

Frizzled-4 Antibody

SPA-04142

Size Price
25 µg Online Inquiry
50 µg Online Inquiry
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Target Information
Target Name Frizzled-4
Gene Abbr. FZD4
Gene ID 8322
Full Name frizzled class receptor 4
Alias CD344, EVR1, FEVR, FZD4S, Fz-4
Introduction This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq]
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-4. Phe37-Glu180. Accession # Q8BLL2.
Usage
Application WB, IHC
Dilutions Western Blot (0.1 µg/mL); Immunohistochemistry (5-15 µg/mL)
Reactivity Mouse
Specificity Detects mouse Frizzled-4 in direct ELISAs and Western Blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant mouse (rm) Frizzled-8 and less than 2% cross-reactivity with rmFrizzled-3 and rmFrizzled-7 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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