FM-381 - CD BioSciences

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FM-381

FM-381

SPC-00895

FM-381

CAS No. 2226521-65-7

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JAK inhibitor

Description
FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.
Product Details
CAS No. CAS No. 2226521-65-7
Description FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.
Formula C24H24N6O2
Molecular Weight 428.49
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN(C)C(=O)C(=CC1=CC=C(O1)C2=NC3=CN=C4C(=C3N2C5CCCCC5)C=CN4)C#N
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.