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FGFR5/FGFRL1 Antibody
SPA-03959
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | FGF Receptor |
| Gene Abbr. | FGFRL1 |
| Gene ID | 53834 |
| Full Name | fibroblast growth factor receptor like 1 |
| Alias | FGFR-5, FGFR5, FHFR |
| Introduction | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | 19 |
| Isotype | IgG |
| Immunogen | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse FGFR5/FGFRL1 (NP_473412.1; Met1-Pro374). |
| Usage | |
|---|---|
| Application | WB, IP |
| Dilutions | Western Blot (1:500-1:2000); Immunoprecipitation (4-6 µL/mg of lysate) |
| Reactivity | Mouse |
| Storage & Handling | |
|---|---|
| Storage Buffer | 0.2 µm filtered solution in PBS. |
| Preservative | No Preservative |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.