Fenofibrate - CD BioSciences

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Fenofibrate

Fenofibrate

SPC-00857

Fenofibrate

CAS No. 49562-28-9

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10 mM (1 mL in DMSO) Online Inquiry
50 mg Online Inquiry
Bulk Size Online Inquiry

PPAR agonist ; P450 (e.g. CYP17) inhibitor ; Autophagy activator

Description
Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.
Product Details
CAS No. CAS No. 49562-28-9
Description Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative. Fenofibrate is a selective agonist of PPARα with EC50 of 30 μM. Fenofibrate binds to and inhibits cytochrome P450 epoxygenase (CYP)2C with IC50 of 0.2 μM, 0.7 μM and 9.7 μM for CYP2C19, CYP2B6 and CYP2C9, respectively. Fenofibrate induces autophagy.
Formula C20H21ClO4
Molecular Weight 360.83
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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